(472) ICU Admission Trends for Esophageal Cancer: Analyzing Trends Among Gastrointestinal Cancers

Introduction: Esophageal cancer (EC) constitutes the fourth most prevalent type of gastrointestinal cancer worldwide. Most patients present EC with advanced-stage disease, resulting in an overall 5-year survival rate of 18%, with ICU admissions being often required. This study aims to analyze ICU admission trends for EC among GI cancer.

Methods: Retrospective analysis was conducted by collecting data from admissions to the Intensive Care Unit (ICU) using the Medical Information Mart for Intensive Care (MIMIC-III) database from 2001 to 2012. Admissions to the ICU with the diagnosis of gastrointestinal cancer (ICD 9 codes: 150-157) were included. Demographics such as gender, age and ethnicity were considered. The data collected included patient demographics, gender, age and ethnicity, as well as hospital stay duration and ICD9 codes. Data was analyzed using IBM SPSS version 24.0 and employing descriptive and inferential statistics.

Results: 2155 adult patients were included in the study, 664 were female (30.7%) and 1491 male (68.8%). The median age for admission to the ICU was 67 years old (58.00 - 77.45), and Caucasians were the most frequent ethnicity (73.7%). 303 patients had the diagnosis of EC, out of which 75.2% were male (228) and 24.8% were female (75). The median age was 64 years (57.30 - 72.18), with Caucasians being the most frequent ethnicity (76.6%).
EC accounts for 14% of admissions to the ICU for gastrointestinal cancer, being the fourth most frequent type of GI cancer. Median ICU stay for both diagnoses is 7-13 days (0 to 6 days - 14 to 20 days).
A Chi-square test was performed, revealing a significant association between the age at which patients are admitted to the ICU and the diagnosis of GI cancer (p < 0.001). This association was also observed in gender (p < 0.001) and ethnicity (p < 0.001).

Conclusions: This study has demonstrated the ICU admission trends of esophageal and other GI cancers. The outcome data indicates a significant correlation between age, gender, and ethnicity with the diagnosis of both esophageal and GI cancers. By considering these demographic factors for personalized treatment, there is a promising potential for improving healthcare outcomes for esophageal cancer.