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Jose Pascual, MD, PhD, FACS, FCCM, FRCSC

University of Pennsylvania

Jose Pascual is a professor of surgery and neurosurgery specialized in trauma and critical care who has a special interest in shock and head injury. He is the Section Chief for Surgical Critical Care for the University of Pennsylvania Health System. His research interests are shared in translational and basic science investigation where he evaluates, through intravital microscopy, the real time microcirculation of the pia in live rodent brains after Traumatic Brain Injury (TBI). He seeks to learn how a variety of insults including head injury, shock and sepsis affect the brain and systemic microcirculation and how different management strategies influence these changes. This basic science work is translated into several clinical projects both retrospective and prospective, evaluating the effects of different neuroprotective agents and strategies in multi-injured and TBI patients across the Penn SICUs, the TSICU and NeuroICUs. He serves in multiple national and international research groups seeking to improve outcomes in polytrauma and traumatic brain injured patients as well as studying the immunemodulating effects of different resuscitation fluids and management strategies in different forms of shock.
Jose Pascual’s research interests also include the dissemination of critical Illness management education utilizing high fidelity simulation. In the last 5 years, this has become heavily weighted out of the Simulation center and into the regular clinical hospital beds, spearheading the now monthly flash (unscheduled), bedside, in situ simulations that are lead and hosted by different groups across the health system (HUP, PPMC) across cardiac, heart & vascular, medical, neuro, trauma and surgical critical care units. Results of this education have been presented at national meetings and several published in peer reviewed journals.

Disclosure information not submitted.

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